UNCONJUGATED ESTRIOL (E3)

The unconjugated estriol (uE3) test measures the level of uE3, an estrogen produced by the placenta during pregnancy, in the blood. This test is used in the second trimester of pregnancy as part of the triple or quadruple screening tests to assess the risk of chromosomal abnormalities such as Down syndrome and Edwards syndrome. Low levels of uE3 can indicate an increased risk of these conditions. The test is valuable for prenatal screening, guiding further diagnostic testing, and ensuring appropriate medical management to support a healthy pregnancy.