BETA 2 GLYCOPROTEIN 1 – IGM

The beta-2 glycoprotein 1 (?2-GP1) IgG test detects IgG antibodies against ?2-GP1, a protein involved in the blood clotting process. This test is used to diagnose anti-phospholipid syndrome (APS), an autoimmune disorder characterized by recurrent blood clots, pregnancy complications, and low platelet counts. Elevated levels of ?2-GP1 IgG antibodies suggest an increased risk of thrombotic events and help guide the diagnosis and management of APS. The test is often performed alongside other anti-phospholipid antibody tests, such as lupus anticoagulant and cardiolipin antibodies, to provide a comprehensive evaluation.