INDIRECT COOMBS TEST

The indirect Coombs test, also known as the indirect antiglobulin test (IAT), detects the presence of antibodies against red blood cells in a person’s serum. This test is used to screen for blood compatibility before transfusions, assess the risk of hemolytic disease of the newborn, and diagnose autoimmune hemolytic anemia. A positive indirect Coombs test indicates the presence of antibodies that may cause red blood cell destruction. The test is valuable for ensuring safe blood transfusions, preventing hemolytic reactions, and managing conditions associated with red blood cell antibodies.