PR3 – ANCA ( C-ANCA )

The proteinase 3 (PR3) antineutrophil cytoplasmic antibodies (ANCA) test detects the presence of PR3-ANCA, also known as c-ANCA, in the blood. This test is used to diagnose and monitor autoimmune vasculitis, such as granulomatosis with polyangiitis (Wegener’s granulomatosis). A positive result indicates an autoimmune response against neutrophils, suggesting vasculitis. The PR3-ANCA test provides valuable information for diagnosing vasculitis, guiding treatment decisions, and monitoring disease activity. It helps ensure appropriate medical intervention and prevent complications associated with autoimmune vasculitis.