ANTI GLOMERULAR BASEMENT MEMBRANE PROTEIN – IgG

The anti-glomerular basement membrane (anti-GBM) IgG test detects the presence of IgG antibodies against the glomerular basement membrane, which is a part of the kidneys filtration system. This test is primarily used to diagnose Goodpasture syndrome, a rare autoimmune disease that affects the kidneys and lungs. Elevated levels of anti-GBM antibodies suggest an immune attack on the glomerular basement membrane, leading to kidney inflammation and damage. The test is crucial for early diagnosis and treatment of Goodpasture syndrome to prevent severe kidney and lung damage. It helps guide the management of the disease, including immunosuppressive therapy.