ANTI DEAMIDATED GLIADIN PEPTIDE – IGA

The anti-deamidated gliadin peptide (DGP) IgA test detects the presence of IgA antibodies against deamidated gliadin peptides, which are associated with celiac disease. Celiac disease is an autoimmune disorder triggered by gluten ingestion, leading to intestinal damage. The anti-DGP IgA test helps diagnose celiac disease, especially in individuals with selective IgA deficiency. Elevated levels of anti-DGP IgA antibodies indicate an immune response to gluten, supporting the diagnosis of celiac disease. This test is used alongside other serological tests, such as tTG-IgA and EMA-IgA, to confirm the diagnosis and monitor adherence to a gluten-free diet.